DNA Binding Motif

						

			
Accessions: CUX1_SRF (HumanTF2 1.0)

			
Names: CUX1_SRF
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 23
Consensus: rCCwTAyAwGGtmrkrATCrATw
Weblogo: 
PSSM: P0      A      C      G      T
01   1676    598   1024    487      r
02    242   3785    168    143      C
03     12   3785      0    375      C
04   3785    534   1144   1943      w
05    660    131     46   3785      T
06   3785    324    712    343      A
07    584   2066    173   1719      y
08   3118     40     96    666      A
09   2437    178    207    963      w
10    232     30   3785      8      G
11    128    108   3785    228      G
12   1180    840    428   2605      t
13   1303   1725    562    195      m
14   1656    531    980    618      r
15    171    180   1162   2271      k
16   1225    142   1885    533      r
17   3785      8     78    135      A
18      5      4     16   3785      T
19     43   3785     18    246      C
20   2001     45   1783      7      r
21   3785      6      5    369      A
22    166      9      2   3785      T
23   1340    370    691   1383      w
Type: Heterodimer
Binding TFs: CUX1_TF1 (Homeobox domain, CUT domain, Homeobox KN domain)
SRF_TF1 / SRF_TF2 (SRF-type transcription factor (DNA-binding and dimerisation domain))
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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