DNA Binding Motif

						

			
Accessions: ERF_EOMES_1 (HumanTF2 1.0)

			
Names: ERF_EOMES
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 29
Consensus: rgGTGtgrvvdhrdwwtvdCACmGGAArb
Weblogo: 
PSSM: P0      A      C      G      T
01    349     72    285    143      r
02    135    156    499     92      g
03      0     73    634     15      G
04     37    184     54    634      T
05     29     10    634      7      G
06    148    174    115    634      t
07     52    158    467    167      g
08    372     50    196     16      r
09    213    203    186     32      v
10    247    169    164     54      v
11    198     71    173    191      d
12    175    186    104    169      h
13    177    108    191    158      r
14    203     57    194    181      d
15    174    105    147    208      w
16    209    125     68    232      w
17     86    116     13    419      t
18    184    176    238     37      v
19    177     70    178    209      d
20     16    606      0     13      C
21    494      5    124     11      A
22     56    634    176     27      C
23    314    320      4     10      m
24      0      0    634      0      G
25      0      1    634      0      G
26    634      0      0     11      A
27    469     12      7    146      A
28    197     56    311     70      r
29     64    186    172    213      b
Type: Heterodimer
Binding TFs: EOMES_TF2 (T-box)
ERF_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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