DNA Binding Motif

						

			
Accessions: 4x9j_A (3D-footprint 20231221)

			
Names: Early growth response protein 1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: EGR-1 with Doubly Methylated DNA
Length: 10
Consensus: annCCCAnnC
Weblogo: 
PSSM: P0      A      C      G      T
01     38     19     19     20      a
02     24     24     24     24      n
03     24     24     24     24      n
04      0     96      0      0      C
05      0     96      0      0      C
06      0     96      0      0      C
07     96      0      0      0      A
08     24     24     24     24      n
09     24     24     24     24      n
10      0     77      0     19      C
Binding TFs: 4x9j_A (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Binding Sites: 4x9j_B
4x9j_C
			
Publications: Zandarashvili L, White MA, Esadze A, Iwahara J. Structural impact of complete CpG methylation within target DNA on specific complex formation of the inducible transcription factor Egr-1. FEBS Lett 589:1748-53 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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