DNA Binding Motif

						

			
Accessions: MA0052.5 (JASPAR 2024)

			
Names: MEF2A
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: ChIP-seq
Length: 10
Consensus: cTAAAAATAG
Weblogo: 
PSSM: P0      A      C      G      T
01   1984  10919   1007   2252      c
02    627   2974    236  12325      T
03  12437   1013   1066   1646      A
04  13132    253    610   2167      A
05  14680    141    506    835      A
06  14453    231    241   1237      A
07  14956    173    202    831      A
08    441    349    215  15157      T
09  15582     50    422    108      A
10   2566   1060  11104   1432      G
Type: Heterodimer
Binding TFs: Q02078 (SRF-type transcription factor (DNA-binding and dimerisation domain), Holliday junction regulator protein family C-terminal repeat)
Q02078
Binding Sites: MA0052.5.1
MA0052.5.10 / MA0052.5.16 / MA0052.5.2 / MA0052.5.3 / MA0052.5.5
MA0052.5.11
MA0052.5.12
MA0052.5.13
MA0052.5.14
MA0052.5.15 / MA0052.5.18
MA0052.5.17
MA0052.5.19 / MA0052.5.20
MA0052.5.4 / MA0052.5.9
MA0052.5.6
MA0052.5.7
MA0052.5.8
			
Publications: Wales S, Hashemi S, Blais A, McDermott JC. Global MEF2 target gene analysis in cardiac and skeletal muscle reveals novel regulation of DUSP6 by p38MAPK-MEF2 signaling. Nucleic Acids Res 42:11349-62 (2014). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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