DNA Binding Motif
| Accessions: | 4r2c_A (3D-footprint 20231221) |
| Names: | Early growth response protein 1 |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Description: | Egr1/Zif268 zinc fingers in complex with hydroxymethylated DNA |
| Length: | 9 |
| Consensus: | GCGTGGGGt |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 0 0 76 20 G 02 0 96 0 0 C 03 0 0 96 0 G 04 0 0 0 96 T 05 0 0 96 0 G 06 0 0 96 0 G 07 0 0 96 0 G 08 0 0 96 0 G 09 20 19 19 38 t |
| Binding TFs: | 4r2c_A (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger) |
| Binding Sites: | 4r2c_B 4r2c_C |
| Publications: | Hashimoto H, Olanrewaju Y.O, Zheng Y, Wilson G.G, Zhang X, Cheng X. Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence. Genes & development 28:2304-13 (2014). [Pubmed] |
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