DNA Binding Motif

						

			
Accessions: MYBL1_HOXA13 (HumanTF2 1.0)

			
Names: MYBL1_HOXA13
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: CTCRTAAAwwakkrmCGTTr
Weblogo: 
PSSM: P0      A      C      G      T
01     44    774     91     25      C
02     44    162     25    722      T
03     47    796      4     76      C
04    208     14    592     10      R
05      8      8      9    797      T
06    791      4      6    191      A
07    799      0      0     26      A
08    796     41     17      2      A
09    486     52     21    308      w
10    288    187    125    200      w
11    310    154    175    161      a
12    170    121    251    258      k
13     72    167    349    212      k
14    425     78    246    118      r
15    337    445     14     57      m
16     84    726     72      0      C
17      4      3    800      3      G
18     10     28     92    792      T
19     10      2     77    800      T
20    359     17    437     31      r
Type: Heterodimer
Binding TFs: HOXA13_TF2 (Homeobox domain, Hox protein A13 N terminal)
HOXA13_Full (Homeobox domain, Hox protein A13 N terminal)
MYBL1_TF1 (Myb-like DNA-binding domain, Myb-like DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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