DNA Binding Motif

						

			
Accessions: HOXB2_ELK1_2 (HumanTF2 1.0), UN0560.1 (JASPAR 2024)

			
Names: HOXB2_ELK1, HOXB2::ELK1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 15
Consensus: TAATkrCCGGAAGTr
Weblogo: 
PSSM: P0      A      C      G      T
01     27     27     13    467      T
02    467     29    157     20      A
03    467     37     21     30      A
04     19     76     41    467      T
05     38    110    175    291      k
06    306     15    161      0      r
07     14    467     52     10      C
08     19    467      1      5      C
09      1      0    467      2      G
10      3      0    467      0      G
11    467      3      5      2      A
12    467     12      8     38      A
13     66     72    467     16      G
14      0     80     36    353      T
15    134     48    189     95      r
Type: Heterodimer
Binding TFs: P19419 (Ets-domain)
ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
HOXB2_TF1 (Homeobox domain)
ELK1_TF1 (Ets-domain)
P19419
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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