DNA Binding Motif

Accessions: HOXB2_ELK1_2 (HumanTF2 1.0), UN0560.1 (JASPAR 2024)
Names: HOXB2_ELK1, HOXB2::ELK1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 15
Consensus: TAATkrCCGGAAGTr
Weblogo:
PSSM: P0 A C G T
01 27 27 13 467 T
02 467 29 157 20 A
03 467 37 21 30 A
04 19 76 41 467 T
05 38 110 175 291 k
06 306 15 161 0 r
07 14 467 52 10 C
08 19 467 1 5 C
09 1 0 467 2 G
10 3 0 467 0 G
11 467 3 5 2 A
12 467 12 8 38 A
13 66 72 467 16 G
14 0 80 36 353 T
15 134 48 189 95 r
Type: Heterodimer
Binding TFs: P19419 (Ets-domain)
ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
HOXB2_TF1 (Homeobox domain)
ELK1_TF1 (Ets-domain)
P19419
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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