DNA Binding Motif

						

			
Accessions: HOXB2_HOXB13_2_3 (HumanTF2 1.0)

			
Names: HOXB2_HOXB13
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 14
Consensus: symATCmmrTAAAm
Weblogo: 
PSSM: P0      A      C      G      T
01    116    325    196     89      s
02     86    286     89    264      y
03    261    464     59     54      m
04    725     52     15     61      A
05      8     49     20    725      T
06      0    725      0     59      C
07    725    350      7     44      m
08    387    725      0    166      m
09    725     21    377     21      r
10      0      0      4    725      T
11    725     43     15    117      A
12    725      0      1      9      A
13    725     28      0      0      A
14    388    247     23     67      m
Type: Heterodimer
Binding TFs: HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
HOXB2_TF1 (Homeobox domain)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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