DNA Binding Motif

						

			
Accessions: HOXA13_MEIS1 (HumanTF2 1.0)

			
Names: HOXA13_MEIS1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: ChIP-Exo; ChIP Exo generated model for binding of MEIS1 with HOX13 type TFs, Immunoprecipitated from T293 Cell line using anti MEIS1 antibody
Length: 14
Consensus: dmyrTAAAaCTGTC
Weblogo: 
PSSM: P0      A      C      G      T
01      3      1      2      2      d
02      3      4      0      2      m
03      2      4      0      3      y
04      5      1      3      0      r
05      0      1      1      7      T
06      7      0      0      0      A
07      7      0      0      0      A
08      7      0      1      0      A
09      4      1      1      1      a
10      0      9      0      1      C
11      0      0      1      7      T
12      0      0     10      0      G
13      1      0      1      7      T
14      0     10      0      0      C
Type: Heterodimer
Binding TFs: HOXA13_TF2 (Homeobox domain, Hox protein A13 N terminal)
HOXA13_Full (Homeobox domain, Hox protein A13 N terminal)
MEIS1_TF1 (Homeobox domain, Homeobox KN domain)
MEIS1_Crystal (Homeobox domain, Homeobox KN domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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