DNA Binding Motif

Accessions: 5e69_A (3D-footprint 20231221)
Names: Glucocorticoid receptor
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Glucocorticoid receptor DNA binding domain - IL8 NF-kB response element complex
Length: 5
Consensus: anaTT
01 54 16 13 13 a
02 24 24 24 24 n
03 57 13 13 13 a
04 0 0 0 96 T
05 0 0 0 96 T
Binding TFs: 5e69_A (Zinc finger, C4 type (two domains))
Binding Sites: 5e69_C
Publications: Hudson WH, Vera IMS, Nwachukwu JC, Weikum ER, Herbst AG, Yang Q, Bain DL, Nettles KW, Kojetin DJ, Ortlund EA. Cryptic glucocorticoid receptor-binding sites pervade genomic NF-κB response elements. Nat Commun 9:1337 (2018). [Pubmed]

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