DNA Binding Motif

Accessions: TEAD4_ALX4_2 (HumanTF2 1.0)
Names: TEAD4_ALX4
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 22
Consensus: rCATwcCkyshTAATyrrATTA
Weblogo:
PSSM: P0 A C G T
01 45 0 82 23 r
02 27 126 14 2 C
03 126 4 8 0 A
04 0 3 3 126 T
05 57 0 39 69 w
06 44 126 46 13 c
07 5 114 6 12 C
08 16 19 36 56 k
09 20 39 14 54 y
10 14 53 33 27 s
11 38 42 9 37 h
12 28 0 2 126 T
13 126 0 2 16 A
14 126 0 6 0 A
15 3 5 2 126 T
16 1 71 9 55 y
17 59 25 68 40 r
18 59 20 43 4 r
19 126 0 23 8 A
20 0 3 0 126 T
21 11 33 0 126 T
22 126 0 0 0 A
Type: Heterodimer
Binding TFs: ALX4_TF2 (Homeobox domain)
TEAD4_TF1 (TEA/ATTS domain family)
ALX4_TF1 (Homeobox domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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