DNA Binding Motif

Accessions: MA2003.2 (JASPAR 2024)
Names: NKX2-4
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: CAP-SELEX
Length: 8
Consensus: cCACTTsA
Weblogo:
PSSM: P0 A C G T
01 385 1185 485 61 c
02 14 1185 7 129 C
03 1185 127 17 207 A
04 0 1185 0 0 C
05 0 25 1 1185 T
06 52 409 13 1185 T
07 243 545 640 58 s
08 1185 56 57 153 A
Type: Heterodimer
Binding TFs: Q9H2Z4 (Homeobox domain)
Q9H2Z4
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

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