DNA Binding Motif

						

			
Accessions: GCM2_PITX1_1 (HumanTF2 1.0)

			
Names: GCM2_PITX1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 14
Consensus: rTrcgGGyGGATTA
Weblogo: 
PSSM: P0      A      C      G      T
01   1421    412    678    135      r
02    192    273    291   2099      T
03    640    195   1459     69      r
04    558   2099    574    460      c
05    459    108   2099    539      g
06     21     11   2099     37      G
07      0      9   2099      9      G
08    304    576    333    887      y
09    423    117   1465     94      G
10     52     63   2099    347      G
11   2099    458    190    205      A
12     16     74     30   2099      T
13    153    335     97   2099      T
14   2099     50    228    325      A
Type: Heterodimer
Binding TFs: GCM2_TF1 (GCM motif protein)
PITX1_TF1 / PITX1_TF2 (Homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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