DNA Binding Motif

Accessions: 6ncm_AB (3D-footprint 20231221)
Names: Forkhead box protein N3
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the human FOXN3 DNA binding domain in complex with a forkhead-like (FHL) DNA sequence
Length: 7
Consensus: TAGCGta
Weblogo:
PSSM: P0 A C G T
01 0 0 0 96 T
02 96 0 0 0 A
03 0 0 96 0 G
04 0 96 0 0 C
05 0 0 96 0 G
06 16 13 13 54 t
07 54 16 13 13 a
Type: Heterodimer
Binding TFs: 6ncm_A (Fork head domain)
6ncm_B (Fork head domain)
Binding Sites: 6ncm_C
6ncm_D
Publications: Rogers JM, Waters CT, Seegar TCM, Jarrett SM, Hallworth AN, Blacklow SC, Bulyk ML. Bispecific Forkhead Transcription Factor FoxN3 Recognizes Two Distinct Motifs with Different DNA Shapes. Mol Cell 74:245-253 (2019). [Pubmed]

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