DNA Binding Motif

						

			
Accessions: 5uhb_F (3D-footprint 20231221)

			
Names: RNA polymerase sigma factor SigA
Organisms: Mycobacterium tuberculosis, strain ATCC 25618 / H37Rv
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with Rifampin
Length: 8
Consensus: TAnaATGG
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0      0     96      T
02     96      0      0      0      A
03     24     24     24     24      n
04     60     12     12     12      a
05     96      0      0      0      A
06      0      0      0     96      T
07      0      0     96      0      G
08      0      0     96      0      G
Binding TFs: 5uhb_F (Sigma-70 factor, region 1.2, Sigma-70 region 3, Sigma-70 region 2 , Sigma-70, region 4)
Binding Sites: 5uhb_G
5uhb_H
			
Publications: Lin W, Mandal S, Degen D, Liu Y, Ebright YW, Li S, Feng Y, Zhang Y, Mandal S, Jiang Y, Liu S, Gigliotti M, Talaue M, Connell N, Das K, Arnold E, Ebright RH. Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol Cell 66:169-179 (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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