DNA Binding Motif

						

			
Accessions: 1pzu_BHIM (3D-footprint 20231221)

			
Names: Nuclear factor of activated T-cells, cytoplasmic 2
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: An asymmetric NFAT1-RHR homodimer on a pseudo-palindromic, Kappa-B site
Length: 26
Consensus: TCCAnnnnGGAAnTTCCAnnnAGGAA
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0      0     96      T
02      0     96      0      0      C
03      0     96      0      0      C
04     80      6      5      5      A
05     24     24     24     24      n
06     24     24     24     24      n
07     24     24     24     24      n
08     24     24     24     24      n
09      0      0     96      0      G
10      0      0     96      0      G
11     96      0      0      0      A
12     80      5      5      6      A
13     24     24     24     24      n
14      6      5      5     80      T
15      0      0      0     96      T
16      0     96      0      0      C
17      0     96      0      0      C
18     80      5      5      6      A
19     24     24     24     24      n
20     24     24     24     24      n
21     24     24     24     24      n
22     80      5      6      5      A
23      0      0     96      0      G
24      0      0     96      0      G
25     96      0      0      0      A
26     80      5      5      6      A
Binding TFs: 1pzu_B / 1pzu_H / 1pzu_I / 1pzu_M (Rel homology domain (RHD), IPT/TIG domain)
Binding Sites: 1pzu_T
1pzu_W
1pzu_X
1pzu_Y
			
Publications: Jin L, Sliz P, Chen L, Macián F, Rao A, Hogan P.G, Harrison S.C. An asymmetric NFAT1 dimer on a pseudo-palindromic kappa B-like DNA site. Nature structural biology 10:807-11 (2003). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.