DNA Binding Motif

Accessions: POU2F1_SOX15_2_3 (HumanTF2 1.0)
Names: POU2F1_SOX15
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: ywtGmATAACAAwrra
Weblogo:
PSSM: P0 A C G T
01 2002 3722 1279 3521 y
02 4454 1963 593 3514 w
03 2343 2182 1408 4590 t
04 1539 577 10524 274 G
05 4104 6421 176 682 m
06 10524 674 16 221 A
07 172 46 202 10524 T
08 10524 1169 2232 430 A
09 10524 213 9 710 A
10 44 10524 1070 1021 C
11 10524 22 72 211 A
12 10524 289 47 105 A
13 5018 288 109 5506 w
14 4317 717 6207 1022 r
15 3690 2059 6835 173 r
16 4873 1939 2153 1559 a
Type: Heterodimer
Binding TFs: POU2F1_TF1 (Homeobox domain, Pou domain - N-terminal to homeobox domain)
SOX15_TF2 (HMG (high mobility group) box, Domain of unknown function (DUF1898))
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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