DNA Binding Motif

						

			
Accessions: ETV5_EVX1_2 (HumanTF2 1.0)

			
Names: ETV5_EVX1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: rsCGGwAATgvbsaTtAr
Weblogo: 
PSSM: P0      A      C      G      T
01    302     94    222    119      r
02    172    255    270     58      s
03    136    525     79     16      C
04      1      3    525      0      G
05     12      0    525      0      G
06    346      8      0    179      w
07    525     11     55     54      A
08    525      0     47      0      A
09     45    118     10    525      T
10     77     61    298     88      g
11    146    138    178     62      v
12    112    141    134    137      b
13    126    187    140     71      s
14    525     49    211     67      a
15     37      4     22    525      T
16    109     92     70    525      t
17    525     36     15    139      A
18    137     84    204    100      r
Type: Heterodimer
Binding TFs: ETV5_TF1 (Ets-domain)
EVX1_TF1 / EVX1_TF2 (Homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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