DNA Binding Motif

						

			
Accessions: TFAP4_DLX3_1 (HumanTF2 1.0)

			
Names: TFAP4_DLX3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: kCAGsTGdvggrsgyaATkr
Weblogo: 
PSSM: P0      A      C      G      T
01    248    286    340    346      k
02     21   1220     23      7      C
03   1220     30      0     52      A
04      0    237   1220    128      G
05    102    855    365      0      s
06     11     33     17   1220      T
07     24      0   1220      0      G
08    403    130    379    308      d
09    342    346    361    171      v
10    256    204    511    249      g
11    275    289    426    230      g
12    329    246    462    182      r
13    180    434    327    279      s
14    381    386   1220    419      g
15     17    519    180   1220      y
16   1220    184    369     53      a
17   1220    188     46     68      A
18     52     15    153   1220      T
19     49    198    482    738      k
20    481     79    738    210      r
Type: Heterodimer
Binding TFs: DLX3_TF2 (Homeobox domain)
TFAP4_TF1 (Helix-loop-helix DNA-binding domain)
TFAP4_Full (Helix-loop-helix DNA-binding domain)
DLX3_Crystal (Homeobox domain)
DLX3_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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