DNA Binding Motif

						

			
Accessions: 5yel_A (3D-footprint 20231221)

			
Names: Transcriptional repressor CTCF
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of CTCF ZFs6-11-gb7CSE
Length: 22
Consensus: ACTGgnnnnnnnnGGTACnGCA
Weblogo: 
PSSM: P0      A      C      G      T
01     86      3      3      4      A
02      0     90      3      3      C
03      3      4     15     74      T
04      0      0     96      0      G
05      3     16     65     12      g
06     24     24     24     24      n
07     24     24     24     24      n
08     24     24     24     24      n
09     24     24     24     24      n
10     24     24     24     24      n
11     24     24     24     24      n
12     24     24     24     24      n
13     24     24     24     24      n
14      1      0     80     15      G
15      0      0     96      0      G
16      0      0      4     92      T
17     87      3      3      3      A
18     16     74      3      3      C
19     24     24     24     24      n
20      0      0     96      0      G
21      0     96      0      0      C
22     92      3      0      1      A
Binding TFs: 5yel_A (Zinc finger, C2H2 type, LIM domain, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
Binding Sites: 5yel_E
5yel_F
			
Publications: Yin M, Wang J, Wang M, Li X, Zhang M, Wu Q, Wang Y. Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites. Cell Res 27:1365-1377 (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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