DNA Binding Motif

						

			
Accessions: ETV2_RFX5_2_3 (HumanTF2 1.0)

			
Names: ETV2_RFX5
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: sryTTCCGGywyrGcAACgr
Weblogo: 
PSSM: P0      A      C      G      T
01    101    240    227    183      s
02    440     41    228     42      r
03      0    443     16    293      y
04    222      0     26    751      T
05     17     34     27    751      T
06      0    751     11      0      C
07      0    751      0      0      C
08     47      4    751     54      G
09     37    124    627    132      G
10    101    188     33    430      y
11    257    153    101    240      w
12    159    248    125    219      y
13    242     84    400     25      r
14    112     69    751     70      G
15    185    751     47    313      c
16    751     52    115     78      A
17    751    120     66     80      A
18     28    751     39     36      C
19    113    162    436     39      g
20    199    153    289    111      r
Type: Heterodimer
Binding TFs: RFX5_TF2 (RFX DNA-binding domain, Poxvirus D5 protein-like)
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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