DNA Binding Motif

Accessions: MA1638.1 (JASPAR 2024)
Names: HAND2
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: ChIP-seq
Length: 10
Consensus: amCAGATGby
Weblogo:
PSSM: P0 A C G T
01 10136 5564 7463 7120 a
02 8836 11298 6994 3155 m
03 19 30062 132 70 C
04 29222 410 647 4 A
05 12 42 30144 85 G
06 30192 30 38 23 A
07 14 2276 31 27962 T
08 234 149 29851 49 G
09 5217 7690 8878 8498 b
10 6165 10227 6108 7783 y
Type: Heterodimer
Binding TFs: P61296 (Helix-loop-helix DNA-binding domain)
P61296
Binding Sites: MA1638.1.1
MA1638.1.10 / MA1638.1.8
MA1638.1.11 / MA1638.1.9
MA1638.1.10 / MA1638.1.12
MA1638.1.11 / MA1638.1.13
MA1638.1.12 / MA1638.1.14
MA1638.1.13 / MA1638.1.15
MA1638.1.14 / MA1638.1.16
MA1638.1.17
MA1638.1.15 / MA1638.1.18
MA1638.1.16 / MA1638.1.19
MA1638.1.2
MA1638.1.17 / MA1638.1.20
MA1638.1.2 / MA1638.1.3
MA1638.1.3 / MA1638.1.4
MA1638.1.4 / MA1638.1.5
MA1638.1.5 / MA1638.1.6
MA1638.1.7
MA1638.1.6 / MA1638.1.8
MA1638.1.9
MA1638.1.18
MA1638.1.19
MA1638.1.20
MA1638.1.7
Publications: Dai Y. S., Cserjesi P. The basic helix-loop-helix factor, HAND2, functions as a transcriptional activator by binding to E-boxes as a heterodimer.. J. Biol. Chem. 277:12604-12612 (2002). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.