DNA Binding Motif

						

			
Accessions: UP00521A_1 (UniPROBE 20160601), UP00530A_1 (UniPROBE 20160601)

			
Names: FOXN2, HTLF, Human T-cell leukemia virus enhancer factor, FoxN2-3_Nvec, N.vec FoxN2/3
Organisms: Homo sapiens, Nematostella vectensis
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 22
Consensus: dtakawsGTAAACAAwkkyrwh
Weblogo: 
PSSM: P0      A      C      G      T
01   0.25   0.22   0.26   0.27      d
02   0.24   0.22   0.24   0.30      t
03   0.35   0.18   0.23   0.25      a
04   0.18   0.16   0.37   0.29      k
05   0.54   0.12   0.11   0.23      a
06   0.33   0.17   0.13   0.37      w
07   0.20   0.26   0.34   0.20      s
08   0.18   0.01   0.81      0      G
09   0.01   0.01      0   0.98      T
10   0.97   0.03      0      0      A
11   0.94   0.03      0   0.03      A
12   0.99      0      0   0.01      A
13      0   0.97      0   0.03      C
14   0.98      0   0.01   0.01      A
15   0.95   0.01   0.01   0.03      A
16   0.50   0.16   0.04   0.29      w
17   0.16   0.23   0.34   0.26      k
18   0.17   0.22   0.25   0.36      k
19   0.11   0.30   0.21   0.39      y
20   0.31   0.12   0.34   0.24      r
21   0.28   0.21   0.19   0.32      w
22   0.28   0.25   0.18   0.29      h
Type: Heterodimer
Binding TFs: UP00521A (Fork head domain)
UP00530A (Fork head domain)
Binding Sites: GTAAACAA
ATAAACAA
ATTGTTTA
GACGCGTC
TAAACAAA
AAAGCGTC
ACCGCGTC
AGACGCCA
AGACGCTA
AGGACGCG
ATAGCGTC
ATCGCGTC
ATGGCGTC
CCGCGTCC
CGACGCTA
GACGCCAA
GACGCTAA
GACGCTAC
GGACGCTA
TAGCGTCA
			
Publications: Nakagawa S, Gisselbrecht SS, Rogers JM, Hartl DL, Bulyk ML. DNA-binding specificity changes in the evolution of forkhead transcription factors. Proc Natl Acad Sci U S A 110:12349-54 (2013). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.