DNA Binding Motif

						

			
Accessions: TEAD4_DLX2_2_3_4_5 (HumanTF2 1.0)

			
Names: TEAD4_DLX2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: crCATwCCryvmTAATtrc
Weblogo: 
PSSM: P0      A      C      G      T
01     84    163     82     95      c
02    203     17    221     15      r
03     67    424     44      3      C
04    424      2     23      2      A
05      6      4      5    424      T
06    215     18     60    424      w
07     21    424     51     24      C
08      7    335     12     69      C
09    121     81    125     97      r
10     86    130     86    120      y
11    107    110    118     89      v
12    110    133    104     77      m
13     63     77     11    424      T
14    424     10     35      0      A
15    424      0      5      0      A
16     25     30     21    424      T
17     89     85    139    424      t
18    208     10    216     28      r
19     64    180    106     75      c
Type: Heterodimer
Binding TFs: DLX2_TF2 (Homeobox domain, Homeobox protein distal-less-like N terminal )
TEAD4_TF1 (TEA/ATTS domain family)
DLX2_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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