DNA Binding Motif

						

			
Accessions: ETV2_FIGLA_2 (HumanTF2 1.0)

			
Names: ETV2_FIGLA
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 22
Consensus: rvCAssTGbtrdacCGGAwgyg
Weblogo: 
PSSM: P0      A      C      G      T
01   1104    691    940    893      r
02   1016    966   1204    442      v
03    157   3618    103     68      C
04   3572    229    190    163      A
05     56   2298   3114    181      s
06    177   2768   2953     84      s
07     87    112     71   3631      T
08     70     86   3620    157      G
09    235   1122   1316    955      b
10    452    809    475   1891      t
11   1865    452   1034    277      r
12   1169    394   1071    993      d
13   2167    208    591    661      a
14   1148   1937    927   1069      c
15    613   3426    196     15      C
16     26     14   3626      8      G
17     38     51   3626    116      G
18   3619     73     77     79      A
19   3216    262     96   1527      w
20    971    342   2499    122      g
21    330   1340    752   2003      y
22    887    631   1375    734      g
Type: Heterodimer
Binding TFs: FIGLA_TF2 (Helix-loop-helix DNA-binding domain)
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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