DNA Binding Motif

						

			
Accessions: 5yj3_CD (3D-footprint 20231221)

			
Names: Telomere zinc finger-associated protein
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of TZAP and telomeric DNA complex
Length: 10
Consensus: tTAGGGtTAG
Weblogo: 
PSSM: P0      A      C      G      T
01     12     10     21     53      t
02      0     11      0     85      T
03     96      0      0      0      A
04      0      0     96      0      G
05      0      0     96      0      G
06      0      0     96      0      G
07     10     23     10     53      t
08      0      0      0     96      T
09     96      0      0      0      A
10      0      0     96      0      G
Type: Heterodimer
Binding TFs: 5yj3_C (Zinc finger, C2H2 type, C2H2 type zinc-finger (2 copies), Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
5yj3_D (Zinc finger, C2H2 type, C2H2 type zinc-finger (2 copies), Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Binding Sites: 5yj3_A
5yj3_B
			
Publications: Zhao Y, Zhang G, He C, Mei Y, Shi Y, Li F. The 11th C2H2 zinc finger and an adjacent C-terminal arm are responsible for TZAP recognition of telomeric DNA. Cell Res 28:130-134 (2018). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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