DNA Binding Motif

						

			
Accessions: SOX2_full_3 (HumanTF 1.0)

			
Names: SOX2
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Notes: Site type: dimeric; SELEX cycle: 4; Possible binding to single stranded DNA
Length: 15
Consensus: aTGAATamCATTCAt
Weblogo: 
PSSM: P0      A      C      G      T
01    467     99    247    188      a
02      8      2      8   1001      T
03      6      2   1001      2      G
04   1001      0      0      3      A
05   1001    123      0      2      A
06      0      0      0   1001      T
07    721     13    191    280      a
08    361    255    179    206      m
09      6   1001      2      0      C
10   1001      2      0      0      A
11      0      1    130   1001      T
12      0      0      0   1001      T
13      0   1001      2      3      C
14   1001     16      6     16      A
15    155    227    102    517      t
Binding TFs: SOX2_full (HMG (high mobility group) box, Domain of unknown function (DUF1898), SOX transcription factor)
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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