DNA Binding Motif

						

			
Accessions: E2F3_ONECUT2_2 (HumanTF2 1.0), UN0493.1 (JASPAR 2024)

			
Names: E2F3_ONECUT2, E2F3::ONECUT2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 19
Consensus: wdsGCGCshwwTATCGAyy
Weblogo: 
PSSM: P0      A      C      G      T
01    670    248    315    670      w
02    556    149    591    608      d
03    238    822   1081    275      s
04     59     17   1903      0      G
05     25   1903     37     33      C
06     18     59   1903      0      G
07      4   1903    122     10      C
08    136    937    966    177      s
09    709    496    160    539      h
10    742    164    267    730      w
11    563    132    126   1082      w
12    245    141     96   1421      T
13   1903      0      0    109      A
14    232     17      0   1903      T
15     31   1903    121    595      C
16     26      0   1903      2      G
17   1903     15     11      0      A
18    113    744    130   1159      y
19    211    701    314    678      y
Type: Heterodimer
Binding TFs: ONECUT2_TF2 (Homeobox domain, CUT domain)
E2F3_TF1 (E2F/DP family winged-helix DNA-binding domain)
ONECUT2_Full (Homeobox domain, CUT domain)
O95948 (Homeobox domain, CUT domain)
O95948
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.