DNA Binding Motif

						

			
Accessions: RFX3_SREBF2 (HumanTF2 1.0)

			
Names: RFX3_SREBF2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: mTrGyAACrTCACGTGAy
Weblogo: 
PSSM: P0      A      C      G      T
01   1174    504     65    144      m
02    243    277     57   1311      T
03    595     24   1293     77      r
04     53    157   1887      0      G
05     32   1066    149    822      y
06   1887      2    134    123      A
07   1887     19    395     20      A
08     94   1887    106    204      C
09   1007    138    671     71      r
10     75      6    123   1887      T
11     25   1887      5      2      C
12   1887      8    394      6      A
13      2   1887    154     12      C
14     13    133   1887      0      G
15     27    190     28   1887      T
16      0     35   1887      3      G
17   1887     60    114    223      A
18      5   1071    169    816      y
Type: Heterodimer
Binding TFs: SREBF2_TF2 (Helix-loop-helix DNA-binding domain)
RFX3_TF1 (RFX DNA-binding domain)
SREBF2_TF1 (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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