DNA Binding Motif

						

			
Accessions: TEAD4_ELK1_2 (HumanTF2 1.0), UN0583.1 (JASPAR 2024)

			
Names: TEAD4_ELK1, TEAD4::ELK1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 14
Consensus: rGAATsCGGAAGyg
Weblogo: 
PSSM: P0      A      C      G      T
01    397      6    722     58      r
02    162     35   1119     30      G
03   1119    146      0    236      A
04   1119      0      5     40      A
05     28      9      0   1119      T
06      0    569    550    205      s
07      0   1119      7     12      C
08      0      6   1119      1      G
09      0      0   1119      0      G
10   1119      7     11     12      A
11   1119     10     14    196      A
12    220     68   1119      9      G
13     93    494     27    625      y
14    223    193    476    227      g
Type: Heterodimer
Binding TFs: ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
TEAD4_TF1 (TEA/ATTS domain family)
Q15561 (TEA/ATTS domain family)
ELK1_TF1 (Ets-domain)
Q15561
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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