DNA Binding Motif

						

			
Accessions: 4is1_CD (3D-footprint 20231221)

			
Names: Zinc finger protein 217
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of ZNF217 bound to DNA
Length: 18
Consensus: TGCAGAATnnATTCTGCA
Weblogo: 
PSSM: P0      A      C      G      T
01      3      6      3     84      T
02      3      3     87      3      G
03      0     96      0      0      C
04     96      0      0      0      A
05      0      0     96      0      G
06     96      0      0      0      A
07     84      3      6      3      A
08      3      3      6     84      T
09     24     24     24     24      n
10     24     24     24     24      n
11     84      3      6      3      A
12      3      3      6     84      T
13      0      0      0     96      T
14      0     96      0      0      C
15      0      0      0     96      T
16      0      0     96      0      G
17     10     80      3      3      C
18     87      3      3      3      A
Type: Heterodimer
Binding TFs: 4is1_C (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
4is1_D (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Binding Sites: 4is1_A / 4is1_B
			
Publications: Vandevenne M, Jacques D.A, Artuz C, Nguyen C.D, Kwan A.H, Segal D.J, Matthews J.M, Crossley M, Guss J.M, Mackay J.P. New insights into DNA recognition by zinc fingers revealed by structural analysis of the oncoprotein ZNF217. The Journal of biological chemistry 288:10616-27 (2013). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.