DNA Binding Motif

						

			
Accessions: MA0047.3 (JASPAR 2024)

			
Names: FOXA2
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: ChIP-seq
Length: 11
Consensus: awGTAAACAww
Weblogo: 
PSSM: P0      A      C      G      T
01 112241  34080  63806  52026      a
02  93740  12432  38538 117443      w
03  18770   2928 236311   4144      G
04   3737   2037   1890 254489      T
05 243805   9424   2641   6283      A
06 223061  22429   6484  10179      A
07 248214   3329   2805   7805      A
08   2411 196969   3603  59170      C
09 246665   3086   2984   9418      A
10  76950  50576  50527  84100      w
11  85410  53633  56632  66478      w
Type: Heterodimer
Binding TFs: Q9Y261 (Fork head domain, Forkhead N-terminal region, HNF3 C-terminal domain)
Q9Y261
Binding Sites: MA0047.3.1
MA0047.3.10 / MA0047.3.11
MA0047.3.11
MA0047.3.12
MA0047.3.13
MA0047.3.14
MA0047.3.15
MA0047.3.16
MA0047.3.17
MA0047.3.18
MA0047.3.19
MA0047.3.2
MA0047.3.20
MA0047.3.2 / MA0047.3.3
MA0047.3.4
MA0047.3.5
MA0047.3.6
MA0047.3.7 / MA0047.3.8
MA0047.3.8 / MA0047.3.9
MA0047.3.10 / MA0047.3.9
MA0047.3.19
MA0047.3.20
MA0047.3.3
MA0047.3.7
			
Publications: Li J, Dantas Machado AC, Guo M, Sagendorf JM, Zhou Z, Jiang L, Chen X, Wu D, Qu L, Chen Z, Chen L, Rohs R, Chen Y. Structure of the Forkhead Domain of FOXA2 Bound to a Complete DNA Consensus Site. Biochemistry 56:3745-3753 (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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