DNA Binding Motif

						

			
Accessions: ELK1_ONECUT2_2 (HumanTF2 1.0)

			
Names: ELK1_ONECUT2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: HT-SELEX; PWM is from validation experiment performed with full-length TFs and is not included into the dendrograms
Length: 17
Consensus: rsCGGAAscGATCGATa
Weblogo: 
PSSM: P0      A      C      G      T
01     44      5     25     10      r
02     13     44     24      7      s
03      3     68     11      0      C
04      3      1     68      2      G
05      4      0     68      1      G
06     68      0      1      7      A
07     68      0      0      4      A
08      0     41     27      3      s
09     11     35     11     12      c
10     10      0     68      0      G
11     65      0      3      0      A
12     13      0      2     68      T
13      2     68     14      0      C
14     13      1     68      0      G
15     68      4      9      9      A
16      7      2      2     68      T
17     68     13     24     10      a
Type: Heterodimer
Binding TFs: ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
ONECUT2_TF2 (Homeobox domain, CUT domain)
ELK1_TF1 (Ets-domain)
ONECUT2_Full (Homeobox domain, CUT domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.