DNA Binding Motif

						

			
Accessions: TFAP2C_MAX_2_3 (HumanTF2 1.0)

			
Names: TFAP2C_MAX
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 31
Consensus: tgsCCysrGGssawrbsssssrrsCACGTGs
Weblogo: 
PSSM: P0      A      C      G      T
01   5901   7469   6108  13804      t
02   3340   3200   4741   2522      g
03    538   5471   8333    788      s
04      0  13804    595     31      C
05     58  13804    571   3201      C
06    390   3958   2153   7302      y
07   2359   4716   4561   2167      s
08   6562   2477   4183    581      r
09   3673    388  13804     25      G
10    178    624  13804     20      G
11    259   9219   4584    578      s
12   2948   3534   4412   2909      s
13   6211   2378   2687   2527      a
14   3589   3337   2276   4601      w
15   4042   3004   3972   2785      r
16   2858   3641   3520   3784      b
17   3112   3681   3922   3088      s
18   3116   3758   4070   2860      s
19   2977   3570   4394   2863      s
20   2905   3899   4099   2901      s
21   3079   3819   4023   2882      s
22   3986   2622   4239   2956      r
23   4902   2605   4197   2099      r
24   2410   4179   4838   2377      s
25    128  13804     33     12      C
26  13804     86     16      8      A
27     21  13804     60    462      C
28    335    105  13804     36      G
29     73    222    186  13804      T
30      6     26  13804    112      G
31   1668   4928   4509   2698      s
Type: Heterodimer
Binding TFs: MAX_TF2 (Helix-loop-helix DNA-binding domain)
TFAP2C_TF1 (Transcription factor AP-2)
MAX_Full (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.