DNA Binding Motif
| Accessions: | UP00521A_3 (UniPROBE 20160601), UP00532A_1 (UniPROBE 20160601) |
| Names: | FOXN2, HTLF, Human T-cell leukemia virus enhancer factor, FoxN2-3_Tadh, T.adh FoxN2/3 |
| Organisms: | Homo sapiens, Trichoplax adhaerens |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Length: | 23 |
| Consensus: | aawswarrkGACGCyAhwwythk |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 0.50 0.15 0.17 0.17 a 02 0.62 0.14 0.11 0.14 a 03 0.40 0.15 0.05 0.41 w 04 0.11 0.48 0.29 0.13 s 05 0.44 0.08 0.16 0.32 w 06 0.40 0.17 0.25 0.19 a 07 0.43 0.06 0.32 0.19 r 08 0.25 0.09 0.49 0.16 r 09 0.20 0.24 0.30 0.25 k 10 0.01 0.02 0.96 0 G 11 0.98 0 0.01 0.01 A 12 0.01 0.97 0 0.02 C 13 0.01 0 0.99 0.01 G 14 0 0.98 0 0.01 C 15 0.02 0.39 0.08 0.52 y 16 0.71 0.07 0.03 0.20 A 17 0.35 0.25 0.03 0.36 h 18 0.44 0.13 0.17 0.26 w 19 0.42 0.16 0.10 0.32 w 20 0.18 0.36 0.05 0.40 y 21 0.24 0.21 0.23 0.32 t 22 0.25 0.29 0.08 0.38 h 23 0.19 0.19 0.36 0.25 k |
| Type: | Heterodimer |
| Binding TFs: | UP00521A (Fork head domain) UP00532A (Fork head domain) |
| Binding Sites: | GTAAACAA ATAAACAA ATTGTTTA GACGCGTC TAAACAAA TGTAAACA TGTATACA AAAGACGC AAAGCGTC AAGCGTCC ACCGCGTC AGACGCCA AGACGCTA AGCGTCAT AGCGTCCC AGCGTCCT AGGACGCG AGGGACGC ATAGCGTC ATCGCGTC ATGGCGTC CCGCGTCC CGACGCTA GACGCCAA GACGCTAA GACGCTAC GAGACGCC GGACGCTA TAGCGTCA |
| Publications: | Nakagawa S, Gisselbrecht SS, Rogers JM, Hartl DL, Bulyk ML. DNA-binding specificity changes in the evolution of forkhead transcription factors. Proc Natl Acad Sci U S A 110:12349-54 (2013). [Pubmed] |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.