DNA Binding Motif

						

			
Accessions: MEIS1_DLX2 (HumanTF2 1.0)

			
Names: MEIS1_DLX2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 14
Consensus: tGACArswTAATtr
Weblogo: 
PSSM: P0      A      C      G      T
01   2540   1745   1216  10866      t
02    415    195  10866    477      G
03  10866    204   1508   2199      A
04    494  10866    180    391      C
05  10866    138   3280    786      A
06   3452   1704   3854   1857      r
07   1720   3628   2915   2602      s
08   3432   1931   1932   3571      w
09   3203   1203    236  10866      T
10  10866    438   1328    275      A
11  10866    144    244     97      A
12   1356   1612   1452  10866      T
13   2192   2140   3193   7673      t
14   5345   1111   5521   1353      r
Type: Heterodimer
Binding TFs: DLX2_TF2 (Homeobox domain, Homeobox protein distal-less-like N terminal )
MEIS1_TF1 (Homeobox domain, Homeobox KN domain)
DLX2_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
MEIS1_Crystal (Homeobox domain, Homeobox KN domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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