DNA Binding Motif

						

			
Accessions: GCM2_ONECUT2 (HumanTF2 1.0)

			
Names: GCM2_ONECUT2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: ATrcGGGyaawmrATCrATa
Weblogo: 
PSSM: P0      A      C      G      T
01   1246     40    197     44      A
02      0     90     10   1443      T
03    594     44    850      0      r
04    295   1443    348    183      c
05    117      4   1443     94      G
06     13      2   1443      2      G
07      0     12   1443      0      G
08    176    613     75    580      y
09    521    248    330    344      a
10    554    309    300    280      a
11    460    292    312    379      w
12    411    384    313    336      m
13    620     53    594    175      r
14   1443    113    265    113      A
15     89      4     15   1443      T
16     28   1443     78    307      C
17    500     13    943     28      r
18   1443      0      0     96      A
19     64     90      6   1443      T
20    641    169    299    335      a
Type: Heterodimer
Binding TFs: GCM2_TF1 (GCM motif protein)
ONECUT2_TF2 (Homeobox domain, CUT domain)
ONECUT2_Full (Homeobox domain, CUT domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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