DNA Binding Motif

Accessions: 3jrd_AB (3D-footprint 20231221)
Names: DNA-binding protein fis
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of Fis bound to 27 bp DNA F25 containing T2A3 sequence at center
Length: 17
Consensus: TGCnCAnnnnnCAnACA
Weblogo:
PSSM: P0 A C G T
01 5 5 7 79 T
02 0 0 96 0 G
03 0 91 0 5 C
04 24 24 24 24 n
05 5 81 5 5 C
06 81 5 5 5 A
07 24 24 24 24 n
08 24 24 24 24 n
09 24 24 24 24 n
10 24 24 24 24 n
11 24 24 24 24 n
12 5 79 5 7 C
13 79 7 5 5 A
14 24 24 24 24 n
15 96 0 0 0 A
16 0 96 0 0 C
17 96 0 0 0 A
Type: Heterodimer
Binding TFs: 3jrd_A (Bacterial regulatory protein, Fis family)
3jrd_B (Bacterial regulatory protein, Fis family)
Binding Sites: 3jrd_C
3jrd_D
Publications: Stella S, Cascio D, Johnson R.C. The shape of the DNA minor groove directs binding by the DNA-bending protein Fis. Genes & development 24:814-26 (2010). [Pubmed]

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