DNA Binding Motif

Accessions: GCM1_FOXO1_1 (HumanTF2 1.0)
Names: GCM1_FOXO1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 14
Consensus: GtmAATAmGGGyrg
Weblogo:
PSSM: P0 A C G T
01 23 5 104 5 G
02 42 10 25 127 t
03 44 83 9 8 m
04 127 15 16 2 A
05 127 2 12 2 A
06 0 2 4 127 T
07 127 2 33 0 A
08 70 56 23 11 m
09 6 7 127 20 G
10 0 2 127 0 G
11 1 1 127 0 G
12 5 42 4 85 y
13 74 12 53 13 r
14 11 23 61 31 g
Type: Heterodimer
Binding TFs: FOXO1_TF1 / FOXO1_TF2 (Fork head domain)
GCM1_TF1 (GCM motif protein)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.