DNA Binding Motif

						

			
Accessions: HOXB13_ONECUT2_1 (HumanTF2 1.0)

			
Names: HOXB13_ONECUT2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: syhrTwAAwATyGAty
Weblogo: 
PSSM: P0      A      C      G      T
01     93    127    105     89      s
02     40    145     77    152      y
03    107    120     21    166      h
04    271      2    143     49      r
05     11     50      6    414      T
06    414     22     35    203      w
07    414      7     21     77      A
08    414     52     14    129      A
09    157     66     55    257      w
10    414     13     26     23      A
11     54      5      9    414      T
12     73    192      0    222      y
13     17     16    414     20      G
14    414     14     41      4      A
15     49    115     45    299      t
16     65    212     31    202      y
Type: Heterodimer
Binding TFs: HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
ONECUT2_TF2 (Homeobox domain, CUT domain)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
ONECUT2_Full (Homeobox domain, CUT domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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