DNA Binding Motif
| Accessions: | MA0830.2 (JASPAR 2024) |
| Names: | TCF4 |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | ChIP-seq |
| Length: | 13 |
| Consensus: | cggCACCTGccss |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 6048 10052 7140 6225 c 02 7034 6754 8618 7059 g 03 4168 5062 18498 1737 g 04 243 28686 321 215 C 05 27023 635 1295 512 A 06 216 26765 1733 751 C 07 356 27724 1197 188 C 08 372 1016 679 27398 T 09 251 540 28432 242 G 10 1694 18935 5281 3555 c 11 5534 12872 4933 6126 c 12 6413 8658 7964 6430 s 13 5133 9843 7662 6827 s |
| Type: | Heterodimer |
| Binding TFs: | P15884 (Helix-loop-helix DNA-binding domain) P15884 |
| Binding Sites: | MA0830.2.10 / MA0830.2.5 MA0830.2.1 MA0830.2.2 MA0830.2.4 / MA0830.2.5 MA0830.2.11 / MA0830.2.6 MA0830.2.12 / MA0830.2.7 MA0830.2.13 / MA0830.2.8 MA0830.2.10 / MA0830.2.14 MA0830.2.15 MA0830.2.16 MA0830.2.17 MA0830.2.18 MA0830.2.19 MA0830.2.11 / MA0830.2.20 MA0830.2.3 MA0830.2.3 / MA0830.2.4 MA0830.2.6 MA0830.2.7 MA0830.2.8 MA0830.2.9 MA0830.2.14 MA0830.2.18 MA0830.2.12 MA0830.2.13 MA0830.2.15 MA0830.2.16 MA0830.2.17 MA0830.2.19 MA0830.2.20 MA0830.2.9 |
| Publications: | Yang J, Horton JR, Li J, Huang Y, Zhang X, Blumenthal RM, Cheng X. Structural basis for preferential binding of human TCF4 to DNA containing 5-carboxylcytosine. Nucleic Acids Res 47:8375-8387 (2019). [Pubmed] |
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