DNA Binding Motif

						

			
Accessions: XylR (DBTBS 1.0)

			
Names: XylR
Organisms: Bacillus subtilis
Libraries: DBTBS 1.0 1
1 Sierro N, Makita Y, de Hoon M, Nakai K. DBTBS: a database of transcriptional regulation in Bacillus subtilis containing upstream intergenic conservation information. Nucleic acids research 36:D93-6 (2008). [Pubmed]
Length: 29
Consensus: AAGTTAGTTTGTTTrAwCAACAAACTAAT
Weblogo: 
PSSM: P0      A      C      G      T
01      2      0      0      0      A
02      2      0      0      0      A
03      0      0      2      0      G
04      0      0      0      2      T
05      0      0      0      2      T
06      2      0      0      0      A
07      0      0      2      0      G
08      0      0      0      2      T
09      0      0      0      2      T
10      0      0      0      2      T
11      0      0      2      0      G
12      0      0      0      2      T
13      0      0      0      2      T
14      0      0      0      2      T
15      1      0      1      0      r
16      2      0      0      0      A
17      1      0      0      1      w
18      0      2      0      0      C
19      2      0      0      0      A
20      2      0      0      0      A
21      0      2      0      0      C
22      2      0      0      0      A
23      2      0      0      0      A
24      2      0      0      0      A
25      0      2      0      0      C
26      0      0      0      2      T
28      2      0      0      0      A
29      0      0      0      2      T
Binding TFs: XylR (ROK family, Winged helix-turn-helix DNA-binding)
Binding Sites: xylA_3
xynP_3
			
Publications: Gärtner D, Geissendörfer M, Hillen W. Expression of the Bacillus subtilis xyl operon is repressed at the level of transcription and is induced by xylose. Journal of bacteriology 170:3102-9 (1988). [Pubmed]


Kreuzer P, Gärtner D, Allmansberger R, Hillen W. Identification and sequence analysis of the Bacillus subtilis W23 xylR gene and xyl operator. Journal of bacteriology 171:3840-5 (1989). [Pubmed]


Gärtner D, Degenkolb J, Ripperger J.A, Allmansberger R, Hillen W. Regulation of the Bacillus subtilis W23 xylose utilization operon: interaction of the Xyl repressor with the xyl operator and the inducer xylose. Molecular & general genetics : MGG 232:415-22 (1992). [Pubmed]


Dahl M.K, Degenkolb J, Hillen W. Transcription of the xyl operon is controlled in Bacillus subtilis by tandem overlapping operators spaced by four base-pairs. Journal of molecular biology 243:413-24 (1994). [Pubmed]


Dahl M.K, Schmiedel D, Hillen W. Glucose and glucose-6-phosphate interaction with Xyl repressor proteins from Bacillus spp. may contribute to regulation of xylose utilization. Journal of bacteriology 177:5467-72 (1995). [Pubmed]


Galinier A, Deutscher J, Martin-Verstraete I. Phosphorylation of either crh or HPr mediates binding of CcpA to the bacillus subtilis xyn cre and catabolite repression of the xyn operon. Journal of molecular biology 286:307-14 (1999). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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