DNA Binding Motif
| Accessions: | 5kl6_A (3D-footprint 20231221) |
| Names: | Wilms tumor protein |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Description: | Wilms Tumor Protein (WT1) Q369R ZnF2-4 in complex with DNA |
| Length: | 10 |
| Consensus: | GCGTGGGGGg |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 0 0 96 0 G 02 0 80 0 16 C 03 0 0 96 0 G 04 0 0 16 80 T 05 0 0 96 0 G 06 0 0 96 0 G 07 0 0 96 0 G 08 0 0 96 0 G 09 0 0 96 0 G 10 16 16 48 16 g |
| Binding TFs: | 5kl6_A (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger) |
| Binding Sites: | 5kl6_B 5kl6_C |
| Publications: | Hashimoto H, Zhang X, Zheng Y, Wilson GG, Cheng X. Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications. Nucleic Acids Res 44:10165-10176 (2016). [Pubmed] |
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