DNA Binding Motif

						

			
Accessions: CLOCK_BHLHA15 (HumanTF2 1.0)

			
Names: CLOCK_BHLHA15
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: wCAYGTGkcyarCAyrTGs
Weblogo: 
PSSM: P0      A      C      G      T
01    486    335    349    452      w
02    201   1622      0      8      C
03   1622      0     15     22      A
04      0   1622     17    554      Y
05    303      5   1622      0      G
06     43    151      9   1622      T
07      3      4   1622    310      G
08    180    332    665    444      k
09    380    818    266    157      c
10    209    497    233    683      y
11    890    216    266    249      a
12    606    405    540     71      r
13     81   1622     85      0      C
14   1622    196     74     44      A
15     33    874    207   1622      y
16   1622    200    870     17      r
17    240    177     23   1622      T
18     23     23   1622    248      G
19     13    608    666    335      s
Type: Heterodimer
Binding TFs: BHLHA15_TF2 (Helix-loop-helix DNA-binding domain)
CLOCK_TF1 / CLOCK_TF2 (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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