DNA Binding Motif

						

			
Accessions: 5lty_K (3D-footprint 20231221)

			
Names: Homeobox protein CDX-2
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Homeobox transcription factor CDX2 bound to methylated DNA
Length: 7
Consensus: tnnTAAa
Weblogo: 
PSSM: P0      A      C      G      T
01     16     13     13     54      t
02     24     24     24     24      n
03     24     24     24     24      n
04      0      0      0     96      T
05     96      0      0      0      A
06     96      0      0      0      A
07     57     13     13     13      a
Binding TFs: 5lty_K (Homeobox domain)
Binding Sites: 5lty_A
5lty_F
			
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.