DNA Binding Motif

						

			
Accessions: 2hot_AB (3D-footprint 20231221)

			
Names: Segmentation polarity homeobox protein engrailed
Organisms: Drosophila melanogaster
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Phage selected homeodomain bound to modified DNA
Length: 10
Consensus: TAATCcnngG
Weblogo: 
PSSM: P0      A      C      G      T
01      3      3      6     84      T
02     84      3      6      3      A
03     96      0      0      0      A
04      6      3      3     84      T
05      0     96      0      0      C
06     14     51     20     11      c
07     24     24     24     24      n
08     24     24     24     24      n
09      3     16     59     18      g
10      0      0     96      0      G
Type: Heterodimer
Binding TFs: 2hot_A (Homeobox domain)
2hot_B (Homeobox domain)
Binding Sites: 2hot_C
2hot_D
			
Publications: Simon M.D, Feldman M.E, Rauh D, Maris A.E, Wemmer D.E, Shokat K.M. Structure and properties of a re-engineered homeodomain protein-DNA interface. ACS chemical biology 1:755-60 (2006). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.