DNA Binding Motif

Accessions: MA0784.2 (JASPAR 2024)
Names: POU1F1
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: CAP-SELEX
Length: 16
Consensus: avCTmATTwGCATAwt
Weblogo:
PSSM: P0 A C G T
01 2016 492 743 876 a
02 1105 1093 1260 668 v
03 131 3623 372 504 C
04 106 126 220 3907 T
05 2281 1846 192 262 m
06 4127 7 28 31 A
07 0 0 1 4127 T
08 91 13 2 4127 T
09 1564 0 0 2563 w
10 419 67 3708 16 G
11 54 4127 1 3 C
12 4127 9 5 17 A
13 3 3 0 4127 T
14 4127 5 5 59 A
15 2323 165 57 1804 w
16 849 702 384 3278 t
Type: Heterodimer
Binding TFs: P28069 (Homeobox domain, Pou domain - N-terminal to homeobox domain)
P28069
Publications: Ingraham H. A., Flynn S. E., Voss J. W., Albert V. R., Kapiloff M. S., Wilson L., Rosenfeld M. G. The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-dependent Pit-1-Pit-1 interactions. Cell 61:1021-1033 (1990). [Pubmed]

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