DNA Binding Motif

						

			
Accessions: TFAP2C_MAX_1 (HumanTF2 1.0)

			
Names: TFAP2C_MAX
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: trsCCysrGGsgrkCACGTGs
Weblogo: 
PSSM: P0      A      C      G      T
01   3186   3709   3121   5970      t
02   1605   1186   2030   1150      r
03    399   2310   3660    397      s
04     11   5970     51     70      C
05     62   5970    188   1905      C
06    354   1812   1331   2473      y
07    930   2039   2107    895      s
08   2319   1258   2036    357      r
09   1208     26   5970     17      G
10     57    319   5970     37      G
11    200   4008   1962    446      s
12   1265   1236   2198   1271      g
13   2820    722   1723    706      r
14   1251   1388   1498   1834      k
15    167   5970     39     54      C
16   5970     40    185    107      A
17     24   5970     73    393      C
18    410     38   5970     24      G
19    124    284     73   5970      T
20     31     49   5970    108      G
21    774   1900   1946   1350      s
Type: Heterodimer
Binding TFs: MAX_TF2 (Helix-loop-helix DNA-binding domain)
TFAP2C_TF1 (Transcription factor AP-2)
MAX_Full (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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