DNA Binding Motif
| Accessions: | 2a66_A (3D-footprint 20231221) |
| Names: | Orphan nuclear receptor NR5A2 |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Description: | Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter |
| Length: | 9 |
| Consensus: | TGnCCTTGA |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 8 11 8 69 T 02 0 0 96 0 G 03 24 24 24 24 n 04 0 96 0 0 C 05 0 96 0 0 C 06 0 8 1 87 T 07 8 11 8 69 T 08 8 8 72 8 G 09 96 0 0 0 A |
| Binding TFs: | 2a66_A (Zinc finger, C4 type (two domains)) |
| Binding Sites: | 2a66_B 2a66_C |
| Publications: | Solomon I.H, Hager J.M, Safi R, McDonnell D.P, Redinbo M.R, Ortlund E.A. Crystal structure of the human LRH-1 DBD-DNA complex reveals Ftz-F1 domain positioning is required for receptor activity. Journal of molecular biology 354:1091-102 (2005). [Pubmed] |
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