DNA Binding Motif

						

			
Accessions: TFAP4_MAX_2 (HumanTF2 1.0)

			
Names: TFAP4_MAX
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: dCAGCTGwbmrgmgCACGTGs
Weblogo: 
PSSM: P0      A      C      G      T
01   3441   2173   3313   3735      d
02    190  12662     78    111      C
03  12662    196    411    655      A
04    209   3059  12662   1125      G
05   1632  12662   2462     40      C
06     91    183    324  12662      T
07      0    141  12662    213      G
08   4219   2252   2988   3203      w
09   1490   3513   3355   4304      b
10   3783   3241   2534   3103      m
11   3446   2190   4176   2849      r
12   3151   2689   3968   2855      g
13   3926   3302   2929   2505      m
14   2271   2706   5185   2500      g
15    207  12662      0     49      C
16  12662     88    417     38      A
17    160  12662    437    487      C
18   1095    462  12662      3      G
19    121    941    209  12662      T
20     61      6  12662    438      G
21   1541   5357   3406   2358      s
Type: Heterodimer
Binding TFs: MAX_TF2 (Helix-loop-helix DNA-binding domain)
TFAP4_TF1 (Helix-loop-helix DNA-binding domain)
TFAP4_Full (Helix-loop-helix DNA-binding domain)
MAX_Full (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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